The Implementation of Pre-exposure Prophylaxis of Injectable Cabotegravir
An Implementation Study of Long-acting Injectable Cabotegravir (CAB-LA) for HIV Pre-Exposure Prophylaxis (PrEP) Among Young MSM, Non-binary and Transgender Persons (The ImPrEP CAB Study)
Evandro Chagas National Institute of Infectious Disease
1,200 participants
Sep 20, 2022
INTERVENTIONAL
Conditions
Summary
Although CAB LA PrEP has been proven efficacious in blinded randomized controlled clinical trials, additional research is needed to evaluate effectiveness in real world settings as well as to identify effective implementation strategies. The proposed implementation study will assess the safety and effectiveness of open label CAB LA PrEP when offered at public health facilities to cisgender men and transgender or gender non-binary individuals who have sex with persons assigned male at birth. The study will also evaluate two nested implementation strategies, an mHealth education and decision support tool and a WhatsApp injection appointment reminder. The study will also assess overall facilitators and barriers to integrating CAB LA into existing oral PrEP services.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
Long action cabotegravir injection
Locations(1)
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NCT05515770