Impact of First-trimester Preeclampsia Screening on Perinatal and Maternal Morbidity (RANSPRE)

This trial is studying whether first-trimester screening for preeclampsia (a dangerous blood pressure condition during pregnancy) — and starting low-dose aspirin for those at high risk — reduces serious complications for mothers and babies in France. You may be eligible if: you are at least 18 years old; you are between 11 and 14 weeks pregnant; you have health insurance; and you have signed the consent form. You may NOT be eligible if: you are outside the 11–14 week window; you have a known miscarriage, ectopic pregnancy, twin pregnancy, or major fetal abnormality; you have had preeclampsia in a previous pregnancy; you have a condition that makes aspirin unsafe (like bleeding disorders, stomach ulcers, or aspirin allergy); or you are already taking regular low-dose aspirin for other reasons. Talk to your doctor to see if this trial is right for you.