RecruitingNCT05522881

The Registry Study of Genetic Alterations of Oropharyngeal Cancer in Taiwan


Sponsor

National Health Research Institutes, Taiwan

Enrollment

410 participants

Start Date

Nov 25, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

We will use the next-generation sequencing (NGS) technology to identify genomic alterations of Taiwanese HPV positive and negative oropharyngeal squamous cell carcinoma (OPSCC) for novel biomarker development and the study design of potential clinical trials or translational research.


Eligibility

Min Age: 20 Years

Plain Language Summary

Simplified for easier understanding

This study is creating a genetic registry of patients in Taiwan with squamous cell carcinoma of the head and neck (particularly throat cancer, oropharyngeal cancer) to understand the role of genetic changes — including HPV (p16) status — in whether cancer comes back after treatment. **You may be eligible if...** - You are 20 years or older - You have been diagnosed with squamous cell carcinoma of the head and neck (confirmed by pathology) - You have tumor tissue available for genetic testing - Your cancer has returned more than 6 months after initial curative treatment (if in the recurrence group) - You have a life expectancy of more than 3 months - You are willing to have regular follow-up **You may NOT be eligible if...** - No tumor tissue is available for genetic testing - You have another active cancer that has required treatment in the past 3 years (with some exceptions) - You are unable or unwilling to provide a complete medical history - Your compliance with the study is uncertain Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(7)

Kaohsiung Medical University Chung-Ho Memorial Hospital

Kaohsiung City, Taiwan

Kaohsiung Veterans General Hospital

Kaohsiung City, Taiwan

China Medical University Hospital

Taichung, Taiwan

Taichung Veterans General Hospital

Taichung, Taiwan

National Cheng Kung University Hospital

Tainan, Taiwan

Pei-Jen Alex Lou

Taipei, Taiwan

Taipei Veterans General Hospital

Taipei, Taiwan

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NCT05522881


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