Oropharynx (OPX) Biomarker Trial

This study collects detailed biological information (biomarkers) from patients with cancers of the throat and mouth area — particularly oropharyngeal cancers related to HPV — to better understand how these tumors behave and how to predict who will respond well to treatment. **You may be eligible if...** - You are 18 or older and able to provide written consent - You have been diagnosed with, or are suspected to have, a cancer or abnormal growth in the head and neck area (including throat, mouth, thyroid, or salivary glands) - You are willing to have your tumor tissue, blood, and/or saliva samples used for research - You can complete questionnaires (alone or with help) **You may NOT be eligible if...** - You are currently enrolled in another cancer treatment trial - You have had another active cancer within the past 5 years (with some exceptions for early-stage or cured cancers) Talk to your doctor to see if this trial is right for you.