RecruitingNot ApplicableNCT05525663

Physical Rehabilitation for Older Patients With Acute Heart Failure With Preserved Ejection Fraction

Physical Rehabilitation for Older Patients With Acute Heart Failure With Preserved Ejection


Sponsor

Wake Forest University Health Sciences

Enrollment

880 participants

Start Date

Feb 16, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The REHAB-HFpEF trial will determine whether a novel physical rehabilitation intervention will improve the primary outcome of combined all-cause rehospitalizations and mortality and the secondary outcome of major mobility disability during 6-month follow-up in patients hospitalized for heart failure and preserved ejection fraction (HFpEF), which is nearly unique to older persons, and for which there are few treatment options.


Eligibility

Min Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a structured physical rehabilitation program during and after a hospital stay can improve recovery in older adults who are admitted for worsening heart failure with preserved ejection fraction (a type of heart failure where the heart squeezes normally but is too stiff). **You may be eligible if...** - You are 60 years or older - You have been hospitalized for more than 24 hours for worsening heart failure - Your heart's squeezing function (ejection fraction) is 45% or higher - You have at least one worsening symptom (like shortness of breath or fatigue) plus at least two signs of fluid buildup confirmed by your doctors - Your treatment has been adjusted specifically to address the heart failure episode **You may NOT be eligible if...** - You do not meet the above criteria for confirmed acute decompensated heart failure - You are below 60 years of age - You have a different type of heart failure (reduced ejection fraction below 45%) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALRehabilitation Intervention

progressive, multi-domain rehabilitation and exercise training intervention


Locations(1)

Atrium Health Wake Forest Baptist

Winston-Salem, North Carolina, United States

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NCT05525663


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