RecruitingNot ApplicableNCT05535192

TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients

TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients (THRIVE-65)


Sponsor

Dana-Farber Cancer Institute

Enrollment

270 participants

Start Date

Mar 20, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This research is being done to assess whether an exercise intervention with protein intake support vs a health education and support program will make it easier for women age 65 or older who are receiving chemotherapy for breast cancer to receive all of their planned chemotherapy according to schedule and at the planned dose.


Eligibility

Sex: FEMALEMin Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a telehealth-based resistance exercise program (strength training done at home via video) can help older women with breast cancer maintain their chemotherapy schedule and overall energy levels. Chemotherapy often causes fatigue and muscle loss that leads doctors to reduce doses, so researchers want to see if exercise can prevent this. **You may be eligible if:** - You are a woman aged 65 or older - You have been diagnosed with stage I–III invasive breast cancer - You are scheduled to receive at least 10 weeks of chemotherapy (before or after surgery) with the goal of cure - Your BMI is between 18 and 50 - You are able to walk for at least 6 minutes - You can read and speak English **You may NOT be eligible if:** - You are male - You are under 65 - Your chemotherapy regimen does not include an anthracycline or taxane drug - You cannot walk or use assistive devices - You cannot understand or speak English Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALTHRIVE

The THRIVE Intervention will involve: 1\) one in-person exercise sessions, followed by twice-weekly, home-based exercise sessions, supervised remotely through telehealth, and 2) a remotely delivered dietary assessment and recommendations to support protein intake throughout the study

BEHAVIORALHealth Education Support Program

Participants will receive a tablet with information and resources regarding mediation, stretching and gentle movement, relaxation and creative arts during chemotherapy


Locations(3)

Dana Farber Cancer Institute

Boston, Massachusetts, United States

Case Western Reserve University/University Hospitals Cleveland

Cleveland, Ohio, United States

University of Pittsburgh

Pittsburgh, Pennsylvania, United States

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NCT05535192


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