RecruitingNCT05543447

DERIVO® 2heal® Study: Clinical Safety and Efficacy of the DERIVO® 2heal® Embolisation Device

DERIVO® 2heal® Study: Clinical Safety and Efficacy of the DERIVO® 2heal® Embolisation Device for Intracranial Aneurysms


Sponsor

Acandis GmbH

Enrollment

158 participants

Start Date

Dec 15, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

To analyse the clinical safety and efficacy of the DERIVO® 2heal® Embolisation Device in the standard clinical routine of flow diversion treatment with respect to the mid- and long-term clinical and angiographic outcomes.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Patient to be treated with DERIVO® 2heal® Embolisation Device due to intracranial aneurysm according to IFU
  • Age > 18 years
  • Signed Informed Consent Form
  • Patient scheduled to be treated for only one target aneurysm except multiple aneurysms located in the same target zone to be treated with one DERIVO® 2heal® Embolisation Device
  • Effective use of antiplatelet medication confirmed by applicable testing method according to local standard

Exclusion Criteria8

  • Previously treated aneurysms with flow diverter, stent or WEB device
  • Treatment as preparation for the flow-diversion treatment does not lead to exclusion of the patient
  • Patient with a ruptured aneurysm in the acute phase of bleeding
  • Pre-treatment disability (mRS > 2)
  • Aneurysms related to pre-existing arteriosclerotic vascular disease in the target vessel
  • Contraindication against treatment with anti-platelet medication
  • Female patient who is known to be pregnant or is breastfeeding or wishes to become pregnant during participation in the study
  • Participating in another study

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Interventions

DEVICEFlow Diverter Treatment with DERIVO 2 Heal Embolisation Device

Flow diversion therapy fpr intracranial aneurysm treatment.


Locations(17)

Universitätsklinikum Augsburg

Augsburg, Germany

Charité - Universitätsmedizin Berlin

Berlin, Germany

Klinikum Bremerhaven-Reinkenheide

Bremerhaven, Germany

Universitätsklinikum Köln

Cologne, Germany

Universitätsklinikum Carl Gustav Carus Dresden

Dresden, Germany

Universitätsklinikum Düsseldorf

Düsseldorf, Germany

Universitätsklinikum Essen

Essen, Germany

Krankenhaus Nordwest Frankfurt

Frankfurt am Main, Germany

Universitätsmedizin Halle

Halle, Germany

Universitätsklinikum Hamburg-Eppendorf

Hamburg, Germany

Westpfalz-Klinikum Kaiserslautern

Kaiserslautern, Germany

Universitätsklinikum Magdeburg

Magdeburg, Germany

Mühlenkreiskliniken | Johannes Wesling Klinikum Minden

Minden, Germany

Ludwig-Maximilians-Universität München

München, Germany

Technische Universität München

München, Germany

Klinikum Vest - Knappschaftskrankenhaus Recklinghausen

Recklinghausen, Germany

Städtisches Klinikum Solingen

Solingen, Germany

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NCT05543447


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