Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis
Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis: a Prospective Registry Study (OCT-ICAS)
jiaoliqun
400 participants
Mar 15, 2020
OBSERVATIONAL
Conditions
Summary
To evaluate the clinical significance of optical coherence tomography (OCT) in interventional treatment of intracranial atherosclerotic stenosis (ICAS).
Eligibility
Inclusion Criteria3
- Symptomatic ICAS. Participants with ICAS with a transient ischaemic attack (TIA) or stroke attributable to the territory of the stenotic artery were defined as symptomatic. A TIA was defined as a transient episode of neurological dysfunction (focal weakness or language disturbance, transient monocular blindness, or required assistance in walking) caused by focal brain or retinal ischaemia that lasted for at least 10 minutes but resolved within 24 hours
- Stenotic degree ≥ 50%, measured by digital subtraction angiography
- The stenosis must located in at least one major intracranial artery (internal carotid artery, vertebral artery, middle cerebral artery, or basilar artery)
Exclusion Criteria2
- Arteriovenous Malformation
- Aneurysm
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Interventions
Intravascular evaluation for vessel wall structure of intracranial atherosclerotic stenosis by application of optical coherence tomography
Percutaneous transluminal angioplasty and stenting will be performed follow the standard or adjusted according to OCT evaluation.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05550077