RecruitingNCT05556395

Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline

Sponsor

Johns Hopkins University

Enrollment

150 participants

Start Date

Apr 1, 2022

Study Type

OBSERVATIONAL

Conditions

Ischemic Stroke

Summary

The goal of this study is to gain a better understanding of why some individuals who have suffered a stroke experience post-stroke cognitive decline. Specifically this study is testing whether global disruption of the blood-brain barrier detected at the time of the stroke is informative about the risk of post-stroke cognitive decline over the next 3 years.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at whether disruption of the blood-brain barrier (the protective layer around the brain) after a stroke is linked to memory and thinking problems that develop over the following months. Researchers will use brain imaging and follow-up cognitive testing to understand this connection. **You may be eligible if:** - You have had an acute ischemic stroke (a stroke caused by a blocked blood vessel) confirmed on MRI, including a perfusion scan **You may NOT be eligible if:** - You are unable to complete telephone-based memory and thinking tests Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.