RecruitingPhase 1NCT05556473

F-Tryptophan PET/CT in Human Cancers

A Pilot Study of 1-(2-[18f]Fluoroethyl)-L-Tryptophan PET/CT Imaging In Human Cancers


Sponsor

Barbara Ann Karmanos Cancer Institute

Enrollment

24 participants

Start Date

Sep 29, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Imaging procedures such as 1-(2-\[18F\]FLUOROETHYL)-L-Tryptophan PET/CT in patients with cancers may help doctors assess a patient's response to treatment and help plan the best treatment in the future. The purpose is to see if there can be a better differentiation of tumor and non-tumor tissue where the tumor tissue has a higher uptake of Tryptophan.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a new type of PET scan that uses a radioactive form of tryptophan (an amino acid) to detect and better characterize various types of cancer, including brain tumors, breast cancer, and neuroendocrine tumors. The scan may help doctors see tumors that are hard to detect with other imaging. **You may be eligible if:** - You are 18 or older - You have a tumor that is at least 1 cm in diameter visible on existing imaging - You can lie still in a PET scanner for about 70 minutes - You are not pregnant or breastfeeding - You have had recent conventional imaging showing visible disease - Specific eligibility also depends on your cancer type (brain tumor, neuroendocrine tumor, or breast cancer) **You may NOT be eligible if:** - You are pregnant or breastfeeding - Your tumor is too small to be detected - You cannot tolerate lying still for the scan Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUG1-(2-[18F]FLUOROETHYL)-L-Tryptophan

Radioactive tracer 1-(2-\[18F\]FLUOROETHYL)-L-Tryptophan 0.14mCi/kg/5MBq/kg injection given one time prior to PET Scan.


Locations(1)

Karmanos Cancer Institute

Detroit, Michigan, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05556473


Related Trials