RecruitingNot ApplicableNCT05557864

Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease

Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease; Udall Project 2 Aims 1 & 2

Sponsor

University of Minnesota

Enrollment

24 participants

Start Date

Aug 25, 2016

Study Type

INTERVENTIONAL

Conditions

Parkinson's Disease

Summary

This protocol will characterize the effects of deep brain stimulation (DBS) location (both adverse and beneficial) on motor signs in people with Parkinson's disease (PD). This information can be used to inform future DBS protocols to tailor stimulation to the specific needs of a patient. If targeted dorsal GP stimulation is shown to significantly improve motor features that are typically resistant to dopamine replacement therapy, these experiments will likely have major impact on clinical practice by providing a potential strategy to these medically intractable symptoms.

Eligibility

Min Age: 21 YearsMax Age: 89 Years

Plain Language Summary

Simplified for easier understanding

This study is examining how the exact placement of a deep brain stimulator (DBS) device within the brain affects motor symptoms in people with Parkinson's disease. Using advanced 7-Tesla MRI scans, researchers aim to find the optimal location for DBS electrodes. **You may be eligible if:** - You have been diagnosed with Parkinson's disease - You have already had a deep brain stimulator implanted in the globus pallidus or subthalamic nucleus - You have existing 7-Tesla MRI brain images available **You may NOT be eligible if:** - You have a significant musculoskeletal condition that affects movement of your arms or legs - You have another major neurological condition - You have dementia or significant cognitive impairment - You have had complications from your DBS surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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