RecruitingNCT05563623

The Beijing Angle Closure Progression Study

The Beijing Angle Closure Progression Study (BAPS)


Sponsor

Peking University People's Hospital

Enrollment

825 participants

Start Date

Aug 4, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The Beijing angle closure progression study (BAPS) aims to explore the 5-year incidence of PACS progressing to PAC or PACG and to determine the possible risk factors of disease progression, which may provide the evidence for choosing the accurate strategies in the management of PACS.


Eligibility

Min Age: 40 YearsMax Age: 75 Years

Inclusion Criteria2

  • "Static" gonioscopy identifying 6 or more clock hours of angle circumference in which the posterior (usually pigmented) trabecular meshwork cannot be seen in both eyes with no peripheral anterior synechiae, and normal intraocular pressure (IOP), optic nerve and visual field.
  • Able to provide informed consent

Exclusion Criteria6

  • Any evidence of primary angle closure (a narrow angle as defined above, but with PAS and/or IOP \> 21 mmHg) or primary angle closure glaucoma (visual field defect or glaucomatous optic neuropathy).
  • Previous intraocular surgery or laser treatment, such as cataract surgery, laser trabeculoplasty, trabeculectomy, laser peripheral iridectomy, and laser iridoplasty
  • Sign of prior acute attack, such as glaucomatous fleck, keratic precipitates, or iris atrophy.
  • Anterior segment structural abnormalities shown by examination, such as iris or ciliary body tumor.
  • Severe health problems precluding follow-up such as end-stage heart disease, kidney disease, or lung disease, or terminal cancer.
  • Severe eye diseases, such as cataract, macular disease, and retinal detachment.

Locations(1)

Peking University People's Hospital

Beijing, Beeijing, China

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NCT05563623


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