RecruitingNCT05565885

Search for BIO Diagnostic and Prognostic Markers in Adult VAScularitis


Sponsor

University Hospital, Tours

Enrollment

225 participants

Start Date

Nov 22, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

To date, there are no reliable diagnostic blood markers of adult vasculitis. To date, the diagnosis of vasculitis is based on invasive procedure, biopsy of affected tissues potentially at risk of complication . In addition, there are no reliable biomarkers to predict the evolution of vasculitis (relapse, refractory form ...) necessary for the management of patients (type of treatment, duration ..) Prospective study, monocentric (CHU de Tours), non-interventional, aimed at finding diagnostic and prognostic biomarkers (both metabolomic and immunologic) in adult vasculitis patients.


Eligibility

Min Age: 16 Years

Inclusion Criteria5

  • Age > 16 years
  • Active vasculitis, new diagnosis or relapse
  • IgA vasculitis
  • ANCA vasculitis
  • Giant cell arteritis

Exclusion Criteria6

  • Person who has objected to the processing of data
  • Pregnant woman
  • Patient positive for HIV, HBV, HCV
  • Treatment in the previous month with corticosteroids, immunosuppressive drugs or biotherapy.
  • Patient unable to understand the information leaflet
  • Adult under guardianship or curatorship

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Interventions

OTHERSampling

4 blood sampling per patient and an additional one in case of relapse


Locations(1)

University hospital

Tours, France

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NCT05565885


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