RecruitingNCT05575167

Single or Repeat Zoledronate Versus Alendronate Following Denosumab (EUROpean Denosumab Effects Consolidation Study)

The Effectiveness of Single or Repeat Zoledronate Infusion Versus Oral Alendronate in Consolidating the Bone Accrual Achieved With Denosumab: a Study Organised by the European Calcified Tissue Society

Sponsor

424 General Military Hospital

Enrollment

125 participants

Start Date

Nov 28, 2023

Study Type

OBSERVATIONAL

Conditions

Osteoporosis, Postmenopausal

Summary

A 24-month prospective, open-label, randomized, multicenter, multinational, non-inferiority pragmatic clinical trial evaluating zoledronate single or double infusion versus oral alendronate following denosumab

Eligibility

Sex: FEMALEMin Age: 50 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Zoledronate or Alendronate for people with osteoporosis, postmenopausal. The study is currently recruiting participants at 9 locations. People eligible for this study include women aged 50 Years to 85 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGZoledronate or Alendronate

infusion (for zoledronate) or oral digestion (for alendronate)

Locations(9)

Univ. Lille, CHU Lille

Lille, France

251 Hellenic Airforce and VA General Hospital

Athens, Greece

First Department of Propaedeutic and Internal Medicine, Medical School, National and Kapodistrian University of Athens

Athens, Greece

, KAT General Hospital

Athens, Greece

424 General Military Hospital

Thessaloniki, Greece

Fondazione IRCCS Cà Granda-Ospedale Maggiore Policlinico

Milan, Italy

Campus Bio-Medico University

Roma, Italy

Department of Medicine, Surgery and Neurosciences, University of Siena

Siena, Italy

University-Hospital S. Maria della Misericordia

Udine, Italy

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NCT05575167

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