RecruitingPhase 4NCT06558188
Combined Anabolic Therapy
Combined Anabolic Therapy Study
Sponsor
Massachusetts General Hospital
Enrollment
50 participants
Start Date
Feb 3, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
In this research study the study investigators want to learn more about the effect of two different FDA-approved medication regimens in the treatment of postmenopausal osteoporosis.
Eligibility
Sex: FEMALEMin Age: 45 Years
Inclusion Criteria3
- women aged 45+
- postmenopausal
- osteoporotic with high risk of fracture
Exclusion Criteria9
- no significant previous use of bone health modifying treatments
- known congenital or acquired bone disease other than osteoporosis
- significant renal disease, liver disease, cardiopulmonary disease, or psychiatric disease
- abnormal calcium or parathyroid hormone level
- serum vitamin D \<20 ng/dL
- anemia (hematocrit \<32%)
- history of malignancy (except non-melanoma skin carcinoma)
- excessive alcohol use or substance abuse
- known contraindications to romosozumab or teriparatide
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Interventions
DRUGRomosozumab
romosozumab 210 milligrams monthly
DRUGTeriparatide
teriparatide 20 micrograms daily
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06558188
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