RecruitingNot ApplicableNCT05575323

Randomized Trial on Same-day SBRT and Surgical Stabilization for Symptomatic Spinal Metastases

Stereotactic Body Radiotherapy and pedicLE Screw fixatioN During One Hospital Visit for Patients With Painful Unstable Spinal Metastases: A Randomized Trial (BLEND)


Sponsor

UMC Utrecht

Enrollment

100 participants

Start Date

Oct 15, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The BLEND RCT aims to evaluate the (cost-)effectiveness of same-day SBRT and surgical stabilization with or without decompression for the treatment of symptomatic, unstable spinal metastases on physical functioning four weeks after the start of treatment, compared with the standard of care (surgery followed by radiotherapy as soon as the wound healed sufficiently).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Same-day SBRT and spinal surgery and Standard of care for people with spinal metastases. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERSame-day SBRT and spinal surgery

SBRT and surgical stabilization with or without decompression within 24 hours

OTHERStandard of care

Surgical stabilization with or without decompression followed by cRT or SBRT as soon as the wound is healed sufficiently


Locations(1)

University Medical Center Utrecht

Utrecht, Netherlands

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NCT05575323


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