RecruitingNCT05589701

Comparing SBRT to CRT in Patients With Spinal Metastases

Prospective Registry Trail COMparing Stereotactic Body Radiotherpy (SBRT) to Conventional PAlliative RadioTherapy (CRT) in Patients With Spinal Metastases


Sponsor

University Health Network, Toronto

Enrollment

100 participants

Start Date

Dec 12, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

This is a single institutional registry-based, prospective, observational study to describe radiation oncologists' decision making during evaluation of patients and to compare real-world outcomes of SBRT vs CRT. A registry-based trial involves observing the effect of something without manipulating it.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria5

  • Adults 18 years of age or older.
  • Patients seen at the Princess Margaret Cancer Centre with painful spinal metastases amenable to radiation treatment.
  • Confirmation of diagnosis: a) Known/documented prior histological cancer diagnosis
  • Able to provide written consent
  • ECOG performance status 0-3

Exclusion Criteria2

  • Prior radiotherapy, with fields overlapping, resulting in excessive doses to organs at risk
  • Lymphoma, myeloma or germ cell malignancies

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Interventions

RADIATIONRadiotherapy

Standard of care radiotherapy administered as per institutional guidelines.


Locations(1)

University Health Network

Toronto, Ontario, Canada

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NCT05589701


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