RecruitingPhase 3NCT05576818

Effect of Synbiotic as an Adjuvant Therapy in the Treatment of Parkinson's Disease

Clinical Study Evaluating the Efficacy and Safety of Synbiotic as an Adjuvant Therapy in the Treatment of Parkinson's Disease


Sponsor

Tanta University

Enrollment

66 participants

Start Date

Jun 30, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to investigate the possible efficacy and safety of synbiotic preparation of Lactobacillus acidophilus probiotic with prebiotic fibers as an adjuvant therapy in the treatment of Parkinson's disease


Eligibility

Min Age: 45 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether taking a synbiotic (a combination of probiotics and prebiotics — beneficial bacteria and the foods that feed them) can improve symptoms and quality of life in people with Parkinson's disease who are already on dopamine replacement medication. **You may be eligible if...** - You are between 45 and 65 years old - You have been diagnosed with Parkinson's disease - You are currently taking dopamine replacement therapy - Your Parkinson's is at a Modified Hoehn and Yahr stage of 1 to 4 **You may NOT be eligible if...** - You have recently taken antibiotics or probiotic products - You have had or are scheduled for gastrointestinal surgery - You have an allergy to probiotics - You have depression, psychosis, hyperthyroidism, or inflammatory conditions - You are a smoker - You take antioxidant or anti-inflammatory medications Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGLactobacillus acidophilus 10 billion colony forming unit (CFU) and prebiotic fibers

Two sachets daily of synbiotic preparation containing Lactobacillus acidophilus 10 billion colony forming unit (CFU) and prebiotic fibers


Locations(1)

Tanta University

Tanta, El Gharbia, Egypt

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NCT05576818


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