RecruitingPhase 2NCT05582161

Efficacy Biomarkers of DAOIB for Dementia


Sponsor

Chang Gung Memorial Hospital

Enrollment

123 participants

Start Date

Oct 3, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This open-label clinical trial will enroll patients with aMCI or mild AD, and they will be treated with DAOIB for 24 weeks. We will assess the patients before entering the study, 8 weeks, 16 weeks, and end point (24 weeks) of the study, and measure blood NMDA and oxidative stress - related biomarkers every 8 weeks. We hypothesize that NMDA and oxidative stress - related biomarkers can predict the efficacy of DAOIB for patients with aMCI or mild AD.


Eligibility

Min Age: 50 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called DAOIB for people with dementia. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 50 Years to 90 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDAOIB

The DAOIB dose will be adjusted every 8 weeks according to clinical evaluation.


Locations(2)

Chang Gung Memorial Hospital

Kaohsiung City, Taiwan

China Medical University Hospital

Taichung, Taiwan

View Full Details on ClinicalTrials.gov

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NCT05582161


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