RecruitingNCT05594706

Anhydroglucitol in Children With Type 1 Diabetes

Anhydroglucitol as a Measure of the Functional Beta-cell Mass in Children With Type 1 Diabetes - Pilot Study

Sponsor

University Hospital, Geneva

Enrollment

60 participants

Start Date

Jan 27, 2023

Study Type

OBSERVATIONAL

Conditions

Diabetes Mellitus, Type 1

Summary

The investigators will measure blood levels of 1,5-anhydroglucitol in children with type 1 diabetes and correlate them with parameters related to functional beta-cell mass in diabetic patients. The values will be compared to those obtained in healthy volunteers. Children with newly diagnosed diabetes as well as children with longstanding disease will be included. The aim of the study is to test the validity of 1,5-anhydroglucitol as a novel biomarker of beta-cell mass and function in type 1 diabetes.

Eligibility

Min Age: 2 YearsMax Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating a blood sugar marker called anhydroglucitol (a measure of short-term glucose spikes) in children with type 1 diabetes who use an insulin pump, to see how well it reflects blood sugar control compared to standard continuous glucose monitors. **You may be eligible if...** - You have type 1 diabetes confirmed by autoantibody testing - You use a continuous subcutaneous insulin pump (CSII), with or without automated insulin delivery - You wear a continuous glucose monitor (CGMS) or flash glucose monitor (FGM) - You are willing to keep using the same type of glucose monitor for the year-long study **You may NOT be eligible if...** - You use multiple daily injections (not an insulin pump) - You plan to change your type of glucose monitor during the study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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