RecruitingNCT05596253

Incidence and Predictors of Post-TIPS Heart Failure in Patients With Cirrhosis

Incidence and Predictors of Post-TIPS (Transjugular Intrahepatic Portosystemic Shunt (TIPS) Heart Failure in Patients With Cirrhosis


Sponsor

West China Hospital

Enrollment

200 participants

Start Date

Oct 11, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to conduct a prospective trial to investigate the incidence of heart failure in cirrhosis patients undergoing transjugular intrahepatic portosystemic shunt ,and to analyze the the predictors and modififications of cardiac function.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria3

  • Cirrhosis
  • TIPS is placed successfully
  • Agree to participate in the trial

Exclusion Criteria7

  • Non-cirrhotic portal hypertension
  • Previous TIPS or surgical shunt
  • Medium to severe pulmonary hypertension
  • Heart failure
  • End-stage renal disease requiring hemodialysis
  • Respiratory failure
  • Malignancies with a life expectancy of less than 6 months

Interventions

PROCEDURETIPS

TIPS: Established distributary channel between the portal vein and hepatic vein via the jugular vein, portal vein blood directly shunts into the systemic circulation to reduce portal vein pressure to effectively prevent bleeding and refractory ascites.


Locations(1)

West China Hospital of Sichuan University

Chengdu, Sichuan, China

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NCT05596253


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