Liver Cirrhosis Clinical Trials

62 recruiting

Liver Cirrhosis Trials at a Glance

67 actively recruiting trials for liver cirrhosis are listed on ClinicalTrialsFinder across 6 cities in 32 countries. The largest study group is Not Applicable with 20 trials, with the heaviest enrollment activity in London, New Delhi, and Vienna. Lead sponsors running liver cirrhosis studies include Institute of Liver and Biliary Sciences, India, European Foundation for Study of Chronic Liver Failure, and Assistance Publique - Hôpitaux de Paris.

Browse liver cirrhosis trials by phase

Treatments under study

About Liver Cirrhosis Clinical Trials

Looking for clinical trials for Liver Cirrhosis? There are currently 62 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Liver Cirrhosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Liver Cirrhosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 67 trials

Recruiting
Phase 2

A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)

Liver Cirrhosis
Boehringer Ingelheim30 enrolled27 locationsNCT07325526
Recruiting
Not Applicable

Early TIPS in Patients With Liver Cirrhosis and Ascites

Liver CirrhosisPortal HypertensionAscites Hepatic
University Hospital Freiburg134 enrolled1 locationNCT06576934
Recruiting

Freiburg TIPS Registry

Liver CirrhosisPortal Vein ThrombosisPortal Hypertension+3 more
University Hospital Freiburg2,000 enrolled1 locationNCT05782556
Recruiting

Exploration of Systemic and Portal Hemostasis in Patients Undergoing Transjugular Intrahepatic Portosystemic Shunt Placement

Liver CirrhosisPortal Hypertension
Assistance Publique - Hôpitaux de Paris45 enrolled1 locationNCT07439939
Recruiting

Utilizing of Physiological Parameters Predict the Prognosis of Cirrhotic Patients With Gastrointestinal Bleeding

Gastrointestinal BleedingLiver Cirrhosis
St. Martin De Porress Hospital150 enrolled1 locationNCT06680583
Recruiting
Not Applicable

Thrombelastometry-guided Blood Component Administration Versus Standard of Care in Patients With Decompensated Liver Cirrhosis Undergoing Invasive Procedures

Liver Cirrhosis With Acute Decompensation
Grigore T. Popa University of Medicine and Pharmacy116 enrolled1 locationNCT07437755
Recruiting
Phase 1

Direct Oral Anticoagulants (Rivaroxaban and Apixaban) in Patients With Liver Cirrhosis

Liver Cirrhosis
Insel Gruppe AG, University Hospital Bern24 enrolled1 locationNCT04874428
Recruiting
Phase 2

Statin and Beta Blocker Use in Patients With Decompensated Cirrhosis

CirrhosisDecompensated Cirrhosis of LiverDecompensated Liver Cirrhosis+1 more
CAMC Health System50 enrolled1 locationNCT06764966
Recruiting
Phase 3

A PROspective Faecal MIcrobiota tranSplantation Trial to Improve outcomEs in Patients With Cirrhosis

Liver Cirrhosis
King's College London300 enrolled23 locationsNCT06461208
Recruiting

The Liver Cirrhosis Cognitive Decline Scale (LiCCoS)

Cognitive DysfunctionLiver CirrhosisNeurocognitive Disorders+1 more
University of Malaya230 enrolled1 locationNCT07418008
Recruiting
Phase 1Phase 2

RTX001 Autologous Engineered Macrophages for Liver Cirrhosis

Liver DiseasesCirrhosis, LiverDecompensated Liver Cirrhosis+5 more
Resolution Therapeutics Limited30 enrolled14 locationsNCT06823713
Recruiting
Not Applicable

Effect of HFNC on Incidence of Hypoxia During Sedated Gastrointestinal Endoscopy in Critical Patients

Liver CirrhosisPolyps of Colon
Zhejiang University450 enrolled3 locationsNCT07252102
Recruiting
Not Applicable

Effect of Handgrip Strength on Portal Vein Hemodynamics in Patients With Liver Cirrhosis

Liver CirrhosisPortal Hypertension
Shanxi Provincial People's Hospital120 enrolled2 locationsNCT07116096
Recruiting
Not Applicable

Underdilated-stent Technique Improves Post-TIPS Encephalopathy

Liver CirrhosisAscites HepaticVariceal Bleeding, Cirrhosis+1 more
The Second Affiliated Hospital of Chongqing Medical University72 enrolled2 locationsNCT07349654
Recruiting

Verification of Risk Factors of Thrombohemorrhagic Complications in Recipients After Related Liver Transplantation

Liver Transplant; ComplicationsLiver Cirrhosis
Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov30 enrolled1 locationNCT06169592
Recruiting

A Comparative Study of MRI and Ultrasound for Detection of Primary Hepatocellular Carcinoma, Body Composition and Risk Factors for Decompensation in Liver Cirrhosis

MRIUltrasoundHepatocellular Carcinoma (HCC)+3 more
Mattias Ekstedt600 enrolled1 locationNCT07291141
Recruiting
Not Applicable

Research on the Protective Effects of Phycocyanin Against Liver Fibrosis and Cirrhosis

Liver CirrhosisLiver Fibrosis
Second Affiliated Hospital, School of Medicine, Zhejiang University10 enrolled1 locationNCT07271576
Recruiting
Not Applicable

Periinterventional Coagulation Management of Patients Undergoing a TIPS

Liver Cirrhosis
Medical University of Graz39 enrolled1 locationNCT04421924
Recruiting

Analysis of Methylomic Features and Prognostic Risk Prediction in Patients With Hepatitis B-related Acute-on-chronic Liver Failure

HBV-related Liver CirrhosisHBV Related Acute-on-chronic Liver FailureHBV (Hepatitis B Virus)
Qilu Hospital of Shandong University100 enrolled1 locationNCT07275554
Recruiting
Phase 4

National Liver Cancer Screening Trial

Liver CancerCarcinoma, HepatocellularLiver Cirrhosis+1 more
University of Texas Southwestern Medical Center5,500 enrolled18 locationsNCT06084234