Health Behavior Change in Midlife Adults at Risk for Alzheimer's Disease
Development of a Personalized Intervention to Motivate Health Behavior Change in Midlife Adults at Risk for Alzheimer's Disease
Rhode Island Hospital
40 participants
Mar 1, 2024
INTERVENTIONAL
Conditions
Summary
Modifying health behaviors like physical activity level, diet, stress, and mental activity level can lower risk for Alzheimer's disease, but many middle-aged and older adults find it difficult to sustain health behavior changes over the long term. This project will develop a new intervention that educates people about Alzheimer's disease risk factors and helps them understand how their personal health beliefs may prevent them from making long-lasting lifestyle changes. The goal is to help people sustain health behavior changes to prevent or delay the onset of Alzheimer's disease and related dementias.
Eligibility
Inclusion Criteria4
- age 45-69 years
- normal cognition (Minnesota Cognitive Acuity Scale \> 52)
- English language fluency
- at least two of the following: i) BMI \> 24.9; ii) systolic blood pressure \> 125 mmHg; iii) LDL cholesterol \> 115 mg/dL; iv) HbA1C \> 6.0%; v) at least one APOE ε4 allele; vi) first-degree relative with AD.
Exclusion Criteria4
- history of serious mental illness (i.e., schizophrenia, bipolar disorder)
- history of neurologic or neurodevelopmental disorder
- current alcohol or drug use disorder based on self-report
- current enrollment in an AD prevention clinical trial.
Interventions
24-session healthy living education program, with enhanced content about health beliefs and mechanisms of behavior change
24-session healthy living education program
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05599425