RecruitingNot ApplicableNCT05599750

Suture Repair vs Mesh Repair for Incisional Hernia

A Modern Comparison of Suture Repair With Mesh Repair for Incisional Hernia


Sponsor

Clayton Petro

Enrollment

154 participants

Start Date

Nov 14, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this randomized controlled trial is to compare the difference in quality of life at one year postoperatively for patients undergoing incisional hernia repair with mesh versus suture repair using modern techniques. The main question it aims to answer are: • Determine if primary suture repair is non-inferior to mesh repair for incisional hernias 2-6cm with respect to quality of life using the HerQLes summary score at one year postoperatively.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study compares two surgical techniques for repairing incisional hernias (hernias that occur at the site of a previous abdominal surgery): suture repair (stitching the hernia closed) versus mesh repair (placing a synthetic patch over the defect). The study aims to find out which method leads to better outcomes, fewer recurrences, and fewer complications for medium-sized hernias. You may be eligible if: - You are over 18 years old - You have an incisional hernia with an expected defect width of 2-6cm - Your surgery is non-emergency - You have previously had abdominal surgery without mesh at the hernia site You may NOT be eligible if: - Your surgery is an emergency - You are pregnant - You previously had a hernia repair with mesh at the same site - Your hernia is smaller than 2cm or larger than 6cm in width - You have a primary (not incisional) hernia - Your wound is classified as contaminated (CDC class II-IV) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREIncisional hernia repair

Participants will undergo incisional hernia repair


Locations(5)

University of Florida

Gainesville, Florida, United States

Northwestern

Chicago, Illinois, United States

Cleveland Clinic Main Campus

Cleveland, Ohio, United States

The Ohio State University Wexner Medical Center

Columbus, Ohio, United States

Vanderbilt University

Nashville, Tennessee, United States

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NCT05599750


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