Treating Emergency Laparotomy Incisions With Negative Pressure Wound Therapy
Uppsala University
720 participants
Dec 16, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to investigate Negative Pressure Wound Therapy (NPWT) in adults undergoing emergency laparotomy. The main question it aims to answer is: Does NPWT decrease wound complications? Researchers will compare it against regular dressings to see if NPWT is superior.
Eligibility
Inclusion Criteria4
- ≥18 years old
- Written informed consent
- \>10 cm midline incision with primary skin closure
- Emergency laparotomy
Exclusion Criteria7
- Not able to consent (e.g. dementia, impaired cognitive function, unconscious)
- Subjects not possible to follow up as assessed by the Investigator
- Allergy to dressing material
- Pregnancy or breastfeeding (females of childbearing potential)
- Previous enrolment in the current study
- Expected reoperation with 28 days of index laparotomy
- Emergency laparotomy within 3 months
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Interventions
Avance Solo Negative Pressure Wound Therapy (NPWT) System is a portable battery powered single use negative pressure system, suitable for use in closed incision and chronic wound indications. The system consists of Avance Solo Pump, Avance Solo Canister 50 mL, Avance Solo Border Dressing and Avance Solo Foam.
Mepilex Border Post-Op is a self-adhesive absorbent surgical dressing designed for exuding wounds. It is intended for acute wounds, such as surgical wounds, cuts and abrasions.
Locations(6)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07003906