Inhaled Corticosteroids (ICS) on Pulmonary Endothelial Function in COPD

This study examines whether adding inhaled corticosteroids (anti-inflammatory inhalers) to standard COPD treatment affects blood vessel function in the lungs of people with moderate COPD. **You may be eligible if...** - You have been diagnosed with COPD by a physician - You have a smoking history of more than 10 pack-years - Your lung function tests show moderate COPD (FEV1 between 50–80% of predicted, FEV1/FVC ratio below 0.7) - You are between 40 and 80 years old - You are already taking a LAMA/LABA (long-acting bronchodilator) combination for at least a month **You may NOT be eligible if...** - You are a woman of childbearing age not using contraception - You are pregnant or breastfeeding - You had a respiratory infection in the past 4 weeks - You recently received a COVID-19 vaccination (within a certain window — check with your doctor) Talk to your doctor to see if this trial is right for you.