RecruitingNCT05632107

Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch ® Monitor

Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch ® Monitor:a Pilot Study


Sponsor

Huazhong University of Science and Technology

Enrollment

100 participants

Start Date

Mar 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

A quantitative neuromuscular monitoring device is desirable to titrate the depth of neuromuscular block (NMB) during a procedure, and to prevent residual effects after removal of the endotracheal tube. Unfortunately, the most widely used monitoring technique acceleromyography (AMG) typically implies a series of cumbersome installation and calibration procedures that frequently precludes correct use of these devices in clinical practice. Electromyography (EMG) has recently attracted a lot of attention as an alternative strategy to compensate for the deficiency of AMG-based neuromuscular monitors. Nowadays, a new technology that allows for the simultaneous acquisition of EMG and AMG signals is commercially available. Although its reliability has been rapidly accepted in Physical Medicine and Rehabilitation, the use of the technique in neuromuscular monitoring has never been reported. The aim of the present study is to assess the validity of the new device for estimating the neuromuscular block by comparing with TOF Watch®-SX, which is the most widely accepted AMG-based neuromuscular monitor that has been practiced in the clinical arena for decades.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Inclusion Criteria4

  • Age less than 18 yr
  • American Society of Anesthesiologists Physical Status I to III
  • Elective surgery requiring muscle relaxation
  • Patients participated voluntarily and signed informed consent

Exclusion Criteria6

  • Patients with known neuromuscular disorder
  • Stroke
  • Patients with a history of allergic reaction toneuromuscular blocking agents
  • Use of medications that might interfere with neuromuscular transmission
  • Any previous injury to the examined arm that might influence nerve conduction parameters
  • Pacemaker

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Interventions

DEVICETOF-Watch®;DELSYS® Wireless surface EMG

TOF-Watch® is the most widely accepted AMG-based neuromuscular monitor; and DELSYS® Wireless surface EMG is a new technology that allows for the simultaneous acquisition of EMG and AMG signals in a wireless manner.


Locations(2)

Department of Anaesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China

Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China

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NCT05632107


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