RecruitingNot ApplicableNCT05632913

Alpha Radiation Emitters Device for the Treatment of Recurrent Lung Cancer

A Feasibility and Safety Study of Intratumoral Diffusing Alpha Radiation Emitters for the Treatment of Recurrent Lung Cancer


Sponsor

Alpha Tau Medical LTD.

Enrollment

10 participants

Start Date

Jul 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for treatment of recurrent Lung Cancer .


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study uses a radiation device called "Alpha DaRT" to treat recurring lung or chest tumors. The device delivers targeted alpha radiation (a type of radiation that travels a very short distance) directly into the tumor to kill cancer cells while minimizing damage to surrounding tissue. **You may be eligible if...** - You have a confirmed recurring tumor in the chest area (mediastinum) - You have up to two treatable tumor lesions - The tumor can be accessed and adequately covered by the radiation seeds - Your doctor has confirmed you are a candidate for this type of radiation treatment **You may NOT be eligible if...** - You have more than two target lesions - The tumor cannot be sufficiently covered by the device - Your doctor has not approved you for interstitial radiation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICERadiation: Diffusing Alpha Radiation Emitters Therapy (DaRT)

An intratumoral insertion of radioactive sources \[Ra-224 containing stainless-steel 316LVM tubes- (Alpha DaRT seeds)\]. The seeds release by recoil into the tumor short-lived alpha-emitting atoms


Locations(1)

Hadassah University Hospital

Jerusalem, Israel

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NCT05632913


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