Glecaprevir/Pibrentasvir for Post-traumatic Stress Disorder

This trial tests whether glecaprevir/pibrentasvir — a medication normally used to treat hepatitis C — might also help reduce symptoms of PTSD (post-traumatic stress disorder) in veterans. Early research suggests this drug may affect stress-related brain pathways. **You may be eligible if...** - You are between 19 and 70 years old and weigh at least 45 kg (about 99 lbs) - You have been diagnosed with PTSD using a standardized assessment within the last week - You are eligible for Veterans Affairs (VA) healthcare - You are using effective birth control if you could become pregnant **You may NOT be eligible if...** - You do not have a confirmed PTSD diagnosis - You are not eligible for VA healthcare - You have liver disease or conditions that make this medication unsafe Talk to your doctor to see if this trial is right for you.