RecruitingPhase 2NCT05641935

Contrast-Enhanced Ultrasound Imaging for Diagnosing Recurrent Renal Cell Carcinoma (RCC) Post Ablation

Multi-Modality Detection of RCC Recurrence Post Ablation


Sponsor

john eisenbrey

Enrollment

210 participants

Start Date

Nov 3, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This phase II trial studies how well contrast-enhanced ultrasound (CEUS) works for diagnosing patients with renal cell cancer (RCC) that has come back (recurrent) after an ablation. Diagnostic imaging, such as CEUS, may help find and monitor long term renal cell cancer recurrence following cryo or microwave ablation.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a contrast-enhanced ultrasound (CEUS) scan can accurately detect if kidney cancer (renal cell carcinoma) has come back after ablation treatment (such as cryotherapy or microwave therapy), potentially as an alternative to CT or MRI scans. **You may be eligible if...** - You previously had cryotherapy or microwave ablation for kidney cancer - You have had, or are scheduled to have, a contrast-enhanced MRI or CT scan to monitor for cancer recurrence within 4 weeks of the ultrasound study - You are 18 years or older and medically stable - If you are a woman of childbearing age, you have a negative pregnancy test **You may NOT be eligible if...** - You are medically unstable or seriously/terminally ill - You have a known allergy to the ultrasound contrast agent (Lumason) - Your medical course is unpredictable Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSulfur Hexafluoride Lipid Microspheres

Given IV

PROCEDUREContrast-Enhanced Ultrasound

Undergo CEUS

PROCEDUREComputed Tomography

Undergo CT

PROCEDUREMagnetic Resonance Imaging

Undergo MRI

OTHERElectronic Health Record Review

Review electronic medical record


Locations(1)

Sidney Kimmel Cancer Center at Thomas Jefferson University

Philadelphia, Pennsylvania, United States

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NCT05641935


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