INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures
The Efficacy of Continuous Intercostal Nerve Blocks in the Treatment of Patients With Multiple Rib Fractures
Zachary Warriner
180 participants
Sep 23, 2025
INTERVENTIONAL
Conditions
Summary
This is a prospective, randomized, non-blinded study comparing CINB plus medical therapy versus standard medical care (non-steroidals and opioids intravenous/oral inpatient and oral outpatient) alone for patients with multiple rib fractures. The objective of this study is to analyze the effect of continuous intercostal nerve block (CINB) in the treatment of patients admitted to the adult trauma service with rib fractures. The effectiveness of CINB as adjunctive treatment will be compared to standard medical therapy involving nonsteroidal and intravenous/oral opioid medications.
Eligibility
Inclusion Criteria4
- Subjects will be at least 18 years old
- Subjects will have 2 or more identified rib fractures
- Subjects will be willing to provide informed consent for procedure
- Subjects will be identified as appropriate for initiation of continuous nerve block therapy for treatment of rib fracture associated pain.
Exclusion Criteria4
- Documented allergy to study medication
- Epidural catheter use
- Prisoners
- Refusal of CINB therapy
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Interventions
Patients in this group will receive CINB (continuous local intercostal infusion of 0.2% Ropivacaine). A single catheter will be placed for short segment involvement and two catheters will be placed in series for longer segments of involvement. If necessary and as part of standard of care, CINB treatment will continue after patient discharge. The administration of CINB therapy will continue in the same manner as inpatient therapy.
Patients in this group receive nonsteroidal and opioid pain medications (intravenous/oral inpatient and oral outpatient) per standard of care.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05642026