Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?
United States Naval Medical Center, San Diego
40 participants
Jan 15, 2023
INTERVENTIONAL
Conditions
Summary
High-energy tibial pilon fractures have historically been associated with poor outcomes largely due to the elevated risk of severe post-traumatic arthritis. Intraarticular fractures result in a pro-inflammatory hemarthrosis that may further exacerbate the chondral damage that was sustained due to the original injury. This project will study the effect of joint lavage on the concentration of inflammatory cytokines in the ankle following a high-energy tibial pilon fracture and the resultant effect on short-term patient outcomes.
Eligibility
Inclusion Criteria3
- Male or female age 18 years or older
- Present with an axially unstable tibial pilon fracture requiring temporary external fixation followed by delayed definitive internal fixation
- Able to give informed consent
Exclusion Criteria11
- Open fractures
- Delayed presentation greater than 72 hours post-injury
- Associated talar body fracture
- Presentation after initial ex-fix placement
- Unreconstructable or unsalvageable joint
- Preexisting ankle arthritis
- Previous ankle surgery
- Contralateral ankle injury
- Age less than 18 years
- Pregnant women
- Individuals who are incarcerated
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Interventions
An arthrotomy will be made at the time of temporary external fixation and 1L normal saline will be used to irrigate the ankle joint.
Locations(1)
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NCT05652881