Tibial Fractures Clinical Trials

11 recruiting

Tibial Fractures Trials at a Glance

12 actively recruiting trials for tibial fractures are listed on ClinicalTrialsFinder across 6 cities in 12 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Nashville, Charlotte, and Houston. Lead sponsors running tibial fractures studies include Wake Forest University Health Sciences, Major Extremity Trauma Research Consortium, and Denver Health and Hospital Authority.

Browse tibial fractures trials by phase

Treatments under study

About Tibial Fractures Clinical Trials

Looking for clinical trials for Tibial Fractures? There are currently 11 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Tibial Fractures trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Tibial Fractures clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Phase 4

Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

Osteomyelitis TibiaTibial FracturesOpen Tibia Fracture
Wake Forest University Health Sciences484 enrolled14 locationsNCT05421741
Recruiting
Phase 3

Intramedullary Calcium Sulfate Antibiotic Depot

Osteomyelitis TibiaTibial FracturesOpen tíbia Fracture
Wake Forest University Health Sciences497 enrolled10 locationsNCT05766670
Recruiting

Zimmer® Natural Nail® (ZNN) Bactiguard Tibia Post-Market Clinical Follow-up Study

Tibial FracturesFracture Infection
Zimmer Biomet500 enrolled16 locationsNCT05022485
Recruiting
Not Applicable

Blood Flow Restriction Training in Patients With Lower Extremity Fractures

Tibial FracturesLower Extremity Fracture
Denver Health and Hospital Authority40 enrolled1 locationNCT06496035
Recruiting
Not Applicable

Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)

Tibial FracturesAcute Compartment SyndromeFracture, Bone
Major Extremity Trauma Research Consortium60 enrolled4 locationsNCT05889559
Recruiting
Phase 3

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

PainTibial Fractures
Major Extremity Trauma Research Consortium1,000 enrolled14 locationsNCT07006675
Recruiting
Not Applicable

Comparison of Healing Measures Tibial Fractures Following Standard Intramedullary Nailing or Micromotion Tibial Intramedullary Nailing

Tibial Fractures
University of Alabama at Birmingham100 enrolled1 locationNCT06679049
Recruiting
Not Applicable

Tibio-talo-calcaneal Fusion by Hindfoot Nail Versus Open Reduction and Internal Fixation in Treatment of Complex Fractures Distal Tibial and Fragility Ankle Fractures in Elderly

Fragility Ankle Fractures and Complex Distal Tibial Fractures
Sohag University40 enrolled1 locationNCT06709365
Recruiting
Not Applicable

Prosthesis Versus Osteosynthesis in Proximal Tibia Fractures

Tibial Fractures
Central Finland Hospital District98 enrolled8 locationsNCT03172715
Recruiting

Management of Closed Diaphyseal Displaced Leg Fractures in Children and Adolescents

Tibial Fractures
University Hospital, Strasbourg, France130 enrolled1 locationNCT06503718
Recruiting
Not Applicable

Intramedullary Bone Grafting for Open Tibial Shaft Fractures

Tibial FracturesNonunion of FractureDelayed Union of Fracture
University of Louisville130 enrolled2 locationsNCT03891888
Recruiting
Not Applicable

Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?

Tibial FracturesPost-Traumatic Osteoarthritis of AnklePost-traumatic; Arthrosis
United States Naval Medical Center, San Diego40 enrolled1 locationNCT05652881