Evaluation of the Use of the FUR to Quantify Tumor Glucose Consumption in Oncologic PET
Evaluation of the Fractional Uptake Rate (FUR) in 18F-FDG PET/CT to Assess Tumour Metabolic Activity
Academisch Ziekenhuis Maastricht
30 participants
Jan 15, 2024
OBSERVATIONAL
Conditions
Summary
The goal of this study is to evaluate the use of new method to quantify the amount of sugar a tumor consumes using PET/CT. The main questions it aims to answer are: * Is the new quantification method superior with respect to the method currently used in the clinic? * Does the new quantification method provide accurate assessment of the sugar consumption of tumours? Participants who will undergo a standard care FDG PET/CT scan will in additional receive a dynamic PET/CT scan prior to the standard care scan. In addition blood samples will be drawn at three time points during the examination.
Eligibility
Inclusion Criteria2
- Patients who receive an 18F FDG PET/CT scan as part of standard care
- Be competent and be 18 years of age or older
Exclusion Criteria7
- Diabetes (fasted blood glucose \> 7 mmol/L)
- Not fasted \> 4 hours
- Physical exercise within 24 hours
- Earlier treatment for carcinoma with radio/chemo-therapy
- Active inflammation (fever \> 38 degrees, CRP \> 5)
- Any condition or medical indication (such as claustrophobia) that indicates that the patient will not be able to lie still for the duration of the dynamic PET/CT examination
- Pregnant or breast feeding
Interventions
Besides the standard care FDG PET/CT examination, subjects receive a dynamic whole body PET/CT examination.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05654675