RecruitingNCT05654675

Evaluation of the Use of the FUR to Quantify Tumor Glucose Consumption in Oncologic PET

Evaluation of the Fractional Uptake Rate (FUR) in 18F-FDG PET/CT to Assess Tumour Metabolic Activity


Sponsor

Academisch Ziekenhuis Maastricht

Enrollment

30 participants

Start Date

Jan 15, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this study is to evaluate the use of new method to quantify the amount of sugar a tumor consumes using PET/CT. The main questions it aims to answer are: * Is the new quantification method superior with respect to the method currently used in the clinic? * Does the new quantification method provide accurate assessment of the sugar consumption of tumours? Participants who will undergo a standard care FDG PET/CT scan will in additional receive a dynamic PET/CT scan prior to the standard care scan. In addition blood samples will be drawn at three time points during the examination.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests a new way to measure how much sugar (glucose) a tumor is consuming using a PET scan. This could help doctors better assess cancer activity and treatment response without needing repeated blood draws. **You may be eligible if...** - You are 18 or older - You are already scheduled to have an FDG PET/CT scan as part of your standard cancer care - You have fasted for at least 4 hours before the scan - You have not exercised in the past 24 hours **You may NOT be eligible if...** - You have diabetes (fasting blood sugar above 7 mmol/L) - You have not fasted before the scan - You have recently had chemo or radiation therapy for cancer - You have an active inflammation or infection (fever, high CRP) - You cannot lie still for the duration of the scan - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTFDG PET/CT

Besides the standard care FDG PET/CT examination, subjects receive a dynamic whole body PET/CT examination.


Locations(1)

Academisch ziekenhuis Maastricht

Maastricht, Limburg, Netherlands

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NCT05654675


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