Lymphoma Clinical Trials
There are 1,426 actively recruiting lymphoma clinical trials across 74 countries. Studies span Phase 2, Phase 1, Not Applicable, Phase 3, Early Phase 1, Phase 4. Top locations include New York, New York, United States, Houston, Texas, United States, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.
Lymphoma Trials at a Glance
1,426 actively recruiting trials for lymphoma are listed on ClinicalTrialsFinder across 6 cities in 74 countries. The largest study group is Phase 2 with 664 trials, with the heaviest enrollment activity in New York, Houston, and Beijing. Lead sponsors running lymphoma studies include National Cancer Institute (NCI), M.D. Anderson Cancer Center, and Ruijin Hospital.
Browse lymphoma trials by phase
Top cities for lymphoma trials
Understanding Lymphoma Clinical Trials
Rituximab (Rituxan), first approved in 1997 after pivotal clinical trials, fundamentally changed the treatment of B-cell lymphomas and remains a cornerstone of therapy decades later. Since then, clinical trials have delivered additional breakthroughs including brentuximab vedotin for Hodgkin lymphoma, polatuzumab vedotin for diffuse large B-cell lymphoma, and CAR-T cell therapies like axicabtagene ciloleucel (Yescarta) for patients with relapsed aggressive lymphoma. With over 70 subtypes of lymphoma, clinical trials are essential for developing treatments tailored to specific disease biology, and many patients with lymphoma have access to promising new therapies only through trial participation.
Why Consider a Clinical Trial?
Frequently Asked Questions
Common questions about Lymphoma clinical trials
Yes. Hodgkin lymphoma and non-Hodgkin lymphoma are biologically distinct diseases with different treatment approaches, so they have separate clinical trials. Non-Hodgkin lymphoma trials are further divided by subtype, such as diffuse large B-cell lymphoma or follicular lymphoma. Your specific subtype determines which trials you are eligible for.
Yes. Some trials focus specifically on patients in remission, studying maintenance therapies or monitoring strategies designed to prevent relapse. There are also survivorship trials that address long-term side effects of treatment. Ask your oncologist about trials that match your current disease status.
It is extremely rare for a lymphoma trial to have a placebo-only group. Most trials compare the new treatment plus standard therapy against standard therapy alone, or compare two active treatments. You will always know before enrolling whether the trial includes a placebo component.
Many trials require a fresh biopsy, especially if your most recent one is older than a few months or if you have received treatment since your last biopsy. This is because lymphoma biology can change over time or after treatment. The biopsy helps confirm your subtype and test for biomarkers that determine trial eligibility.
Many academic cancer centers offer virtual pre-screening consultations to determine if you might qualify before you travel. Some trials allow portions of treatment and monitoring to be done at a local oncologist through satellite site arrangements. Ask the trial coordinator about remote participation options and travel reimbursement programs.
Showing 1–20 of 1,426 trials