RecruitingNCT05657483

Inflammatory Index as a Predictor for Endometrial Cancer: an Observational Study

Sponsor

University of Campania Luigi Vanvitelli

Enrollment

128 participants

Start Date

Dec 10, 2022

Study Type

OBSERVATIONAL

Conditions

Endometrial Neoplasms Inflammatory Response

Summary

It is a prospective observational trial. Primary goal is identification of an association between alteration of systemic inflammation indices, such as neutrophil-to-lymphocyte ratio (NLR), platelet-t- lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (MRL) and patients risk classification according to European Guidelines. The population is represented by all women being admitted to the Gynecology Ward, through Emergency, who are affected by endometrial cancer. Participants will undergo surgery, and freely express their consent to participate in the study.

Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This observational study examines whether blood test markers that reflect inflammation levels can predict the stage and severity of endometrial (uterine) cancer at the time of diagnosis, potentially helping to improve pre-surgical planning. **You may be eligible if...** - You have been diagnosed with endometrial cancer confirmed by biopsy - You are scheduled to have surgery for cancer staging - You had a full-body CT scan within 30 days before joining the study - You are at least 18 years old **You may NOT be eligible if...** - You have a chronic inflammatory condition such as inflammatory bowel disease or a rheumatic condition - You have been diagnosed with another cancer in the last 3 years - You have been on steroid therapy in the 30 days before joining - You are not mentally or legally fit to participate (unfit to plead) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTVenous blood sample

Blood chemistry tests: neutrophil; lymphocyte; monocyte; platelet counts.

OTHERSurgical staging of endometrial cancer

Endometrial, adnexal, and lymphoid tissue samples.

Locations(1)

Università degli Studi della Campania Luigi Vanvitelli

Naples, Italy

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