RecruitingNCT05671887

DREAM: Double Lung Transplant REgistry Aimed for Lung-limited Malignancies

Double Lung Transplant REgistry Aimed for Lung-limited Malignancies (DREAM) - a Prospective Observational Registry Study for Patients Undergoing Lung Transplantation for Medically Refractory Cancers Confined to the Lungs


Sponsor

Northwestern University

Enrollment

125 participants

Start Date

Nov 16, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

This is a prospective observational registration trial for patients who undergo lung transplantation for the treatment of the select groups of medically refractory cancers affecting the lungs alone without extrapulmonary nodal and distant metastasis.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This registry study collects information on patients who receive a double lung transplant for lung-only cancers (such as certain types of lung cancer or mesothelioma). The goal is to track long-term outcomes and understand whether this aggressive but potentially curative treatment strategy can be offered more broadly. **You may be eligible if...** - You are an adult (up to age 80) - You are undergoing a double lung transplant at a participating clinical program - Your cancer is limited to the lungs (no disease outside the chest) - Standard treatments have been exhausted or are not available - You are in good enough health to tolerate a major transplant surgery **You may NOT be eligible if...** - Your cancer has spread outside the lungs - You are not medically fit for the transplant procedure - You have not exhausted standard treatment options - You are unwilling to participate in the registry Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREDouble Lung Transplantation

To evaluate outcomes among patients who undergo lung transplantation for treatment of a select group of medically refractory cancers affecting the lungs alone without extrapulmonary nodal and distant metastasis.


Locations(1)

Thoracic Surgery, Canning Thoracic Institute (Northwestern Memorial Hospital)

Chicago, Illinois, United States

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NCT05671887


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