Lung Transplant Clinical Trials

62 recruitingLast updated: June 18, 2026

There are 62 actively recruiting lung transplant clinical trials across 28 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 4, Early Phase 1, Phase 3. Top locations include Toronto, Ontario, Canada, New York, New York, United States, Jacksonville, Florida, United States. Updated daily from ClinicalTrials.gov.


Lung Transplant Trials at a Glance

62 actively recruiting trials for lung transplant are listed on ClinicalTrialsFinder across 6 cities in 28 countries. The largest study group is Not Applicable with 21 trials, with the heaviest enrollment activity in Toronto, New York, and Jacksonville. Lead sponsors running lung transplant studies include Mayo Clinic, University Health Network, Toronto, and Lund University Hospital.

Browse lung transplant trials by phase

Treatments under study

About Lung Transplant Clinical Trials

Looking for clinical trials for Lung Transplant? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Lung Transplant trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Lung Transplant clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 62 trials

Recruiting

GRAfT 2.0. A Multimodal Prospective Approach to Define the Mechanisms and Clinical Features of Acute and Chronic Rejection in Lung Transplantation

end stage lung diseaseLung TransplantRejection
National Heart, Lung, and Blood Institute (NHLBI)100 enrolled1 locationNCT07516379
Recruiting
Phase 2

Tocilizumab in Lung Transplantation

Lung Transplant
National Institute of Allergy and Infectious Diseases (NIAID)350 enrolled21 locationsNCT06033196
Recruiting
Not Applicable

Evaluating the Impact of Cryo-analgesia on Recovery After Double Lung Transplantation

Lung Transplant; Pain
University Hospital, Gasthuisberg40 enrolled1 locationNCT06959056
Recruiting

Trifecta-Lung cfDNA-MMDx Study

Lung transplantation
University of Alberta600 enrolled19 locationsNCT05837663
Recruiting
Phase 3

A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction

Lung Transplant Rejection
Sanofi180 enrolled80 locationsNCT06082037
Recruiting
Phase 2

CMV Immunity Monitoring in Lung Transplant Recipients

Lung Transplant; Complications
NYU Langone Health50 enrolled1 locationNCT05708755
Recruiting

Diagnostic and Therapeutic Applications of Microarrays in Lung Transplantation

Lung Transplant Rejection
University of Alberta700 enrolled11 locationsNCT02812290
Recruiting
Early Phase 1

Early Use of Long-acting Tacrolimus in Lung Transplant Recipients

Lung Transplant; Complications
Vanderbilt University Medical Center48 enrolled1 locationNCT04469842
Recruiting
Phase 2

LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome.

Bronchiolitis Obliterans SyndromeLung transplantationChronic lung allograft dysfunction
Steven Hays, MD30 enrolled1 locationNCT06018766
Recruiting
Phase 2

Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant Recipients

Lung Transplant
National Institute of Allergy and Infectious Diseases (NIAID)234 enrolled12 locationsNCT06476132
Recruiting

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

Lung Transplant; ComplicationsLung Transplant; Infection or InflammationLung Transplant Rejection+1 more
Duke University2,600 enrolled19 locationsNCT06399302
Recruiting
Not Applicable

Cryoprobe Biopsy and Chronic Rejection in Lung Transplant Recipients

Lung Transplant Rejection
Mayo Clinic100 enrolled1 locationNCT06824402
Recruiting
Not Applicable

A Study of Venoarterial ECMO vs Off-Pump Bilateral Orthotopic Lung Transplantation

Lung Transplant
Mayo Clinic228 enrolled3 locationsNCT05547698
Recruiting
Not Applicable

Pre-transplant Health Coaching to Improve Patient-Reported Outcomes in Lung Transplant Candidates

Lung Transplant
Mayo Clinic230 enrolled3 locationsNCT05426200
Recruiting
Phase 1

Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension

Lung TransplantPulmonary Hypertension
Mayo Clinic4 enrolled1 locationNCT06770023
Recruiting
Phase 2

Developing Hyperpolarized Gas MRI Signatures to Detect and Manage Acute Cellular Rejection

Lung Transplant Rejection
University of Virginia60 enrolled1 locationNCT07046910
Recruiting

Association Between Renal Regional Oxygen Saturation Measured by Near-InfraRed Spectroscopy and Postoperative Renal Failure After Lung Transplantation Surgery: A Pilot Study

Lung Transplant; ComplicationsAcute Kidney Injury
Assistance Publique Hopitaux De Marseille80 enrolled1 locationNCT05836922
Recruiting
Phase 4

Combination Letermovir and Standard of Care Antiviral for Enhanced Antiviral Response in Cytomegalovirus Infection in Lung Transplant Recipients

CMVLung Transplant Recipient
University Health Network, Toronto40 enrolled1 locationNCT07235683
Recruiting
Not Applicable

Lung Ultrasound Artefact Analysis for Exclusion of Acute Rejection in Lung Transplant Recipients

Post-Lung Transplantation Bronchiectasis
Mayo Clinic90 enrolled1 locationNCT04582279
Recruiting
Phase 2

This Study is Assessing the Safety and Efficacy of Immune Inhibition as a Treatment to Prevent Primary Graft Dysfunction

Acute Lung Injury(ALI)Natural Killer Cell Mediated ImmunityPrimary Graft Dysfunction+1 more
University of California, San Francisco120 enrolled1 locationNCT06853223