RecruitingNot ApplicableNCT05675969

Pilot Study of Microvesicles in Pre-eclamptic and Non-pre-eclamptic Women With Threatened Preterm Delivery

Study of Microvesicles in Pre-eclampsia


Sponsor

University Hospital, Bordeaux

Enrollment

20 participants

Start Date

May 31, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

A large number of studies on MVs from syncytiotrophoblasts support the hypothesis of their involvement in pre-eclampsia, via their multiple effects, among others as pro-coagulant, immuno-stimulatory and anti-angiogenic factors. The main objective is to compare the total concentration of the main populations of MVs in the maternal blood of a population of pre-eclamptic patients to those of a population of non-pre-eclamptic patients.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating tiny particles in the blood called microvesicles in pregnant women who are at risk of early labor. Researchers want to understand whether these particles differ between women with and without preeclampsia (a serious pregnancy complication involving high blood pressure), which could help develop better diagnostic tools. **You may be eligible if...** - You are at least 18 years old - You are pregnant with a single baby, between 23 and approximately 32 weeks along - You are hospitalized for threatened preterm labor without signs of infection (non-preeclampsia group), OR you have been diagnosed with severe preeclampsia before 32 weeks (preeclampsia group) **You may NOT be eligible if...** - You are unable to understand what the study involves or decline to participate - You are under legal protection that limits your ability to consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERBlood sample

Collection of 2 additional tubes of 4.5mL of citrate blood


Locations(1)

CHU Bordeaux

Bordeaux, France

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NCT05675969


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