Fecal Microbiota Transplantation in Pediatric Ulcerative Colitis (UC)

This study is testing fecal microbiota transplantation (FMT) — a procedure where healthy donor stool is transferred to a patient to restore healthy gut bacteria — as a treatment for children with ulcerative colitis (UC), an inflammatory bowel disease. It includes both newly diagnosed children and those whose UC hasn't responded to standard therapies. **You may be eligible if...** - Your child is between 2 and 16 years old with no genetic diseases - Your child has been diagnosed with mild to moderate ulcerative colitis - Your child is either newly diagnosed (first-line group) or has not responded to standard treatments like steroids, immunosuppressants, or biologics (refractory group) - Your child and family are willing to undergo regular colonoscopies **You may NOT be eligible if...** - Your child has been on exclusive tube feeding (PEN) for less than 8 weeks - Your child has already received standard medications like steroids, methotrexate, or anti-TNF agents as first-line treatment (for the first-line group) - There are contraindications to all FMT delivery methods (tube, scope, or enema) - Consent or assent cannot be provided Talk to your doctor to see if this trial is right for you.