40 Hz Light Neurostimulation for Patients With Depression (FELIX)

This study — called FELIX — is testing whether a light therapy device that delivers flickering 40 Hz light stimulation can help reduce symptoms of depression when used at home for 1 hour a day over 6 weeks. The therapy works by stimulating brain activity at a specific frequency linked to improved brain function. **You may be eligible if...** - You are between 18 and 75 years old - You have been diagnosed with major depression and are currently experiencing a depressive episode - Your depression score meets the required severity threshold - You have been on stable medication or therapy for at least 4 weeks before starting the trial - You are able and willing to use the device for 1 hour per day for 6 weeks **You may NOT be eligible if...** - You have a history of photosensitive migraines or epileptic seizures - You have a known eye disorder that could be worsened by light - You have bipolar disorder or current psychotic symptoms - You have active suicidal thoughts - You have a current drug or alcohol dependence - You have a history of borderline personality disorder - You are pregnant Talk to your doctor to see if this trial is right for you.