Evaluation of the Effect of Systemic Proteolytic Enzyme Therapy on Postoperative Inflammatory Response and QoL After Surgical Extraction of Impacted Mandibular Third Molars

This study is testing whether a systemic enzyme therapy (a supplement containing natural enzymes) can reduce inflammation, swelling, and pain after the surgical removal of an impacted lower wisdom tooth — and whether it improves recovery and quality of life afterward. **You may be eligible if...** - You are a healthy adult (18 or older) - You have an impacted lower wisdom tooth that needs to be surgically removed - Your impacted tooth is classified as moderately to partially impacted (Pell and Gregory Class I or II, Position A or B) - You are healthy enough to tolerate the surgery **You may NOT be eligible if...** - You have uncontrolled systemic diseases - You have had chemotherapy or radiation to the head/neck region - You have an active infection at the surgery site - Your wisdom tooth is associated with a cyst or tumor - Your tooth is fully or deeply impacted (Pell and Gregory Class III, Position C) Talk to your doctor to see if this trial is right for you.