RecruitingNCT05681858

Plaque Burden and Ischemia in MINOCA

Coronary Artery Plaque, Perivascular Inflammation and Myocardial Ischemia in Patients With Myocardial Infraction and Non-obstructive Coronary Arteries


Sponsor

University of Bergen

Enrollment

100 participants

Start Date

Aug 15, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this clinical trial is to assess coronary artery plaque burden, perivascular inflammation and extent of myocardial ischemia in patients presenting with acute myocardial infarction and non-obstructive coronary artery disease. The main question it aims to answer are: * Identify coronary artery anatomy, plaque burden, composition and high-risk plaque features by CT coronary angiography in MINOCA * Assess presence, extent and severity of myocardial ischemia in MINOCA Participants will examined by CT coronary angiography and stress \[12N\] NH3 PET-MR.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Acute chest pain
  • Elevated troponin
  • Non-obstructive coronary arteries by coronary angiography

Exclusion Criteria3

  • Obstructive coronary artery disease
  • Contraindications against CT coronary angiography or stress \[12N\] NH3 PET-MR
  • Not able to give informed consent

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Interventions

DIAGNOSTIC_TESTCT coronary angiography and [12N] NH3 PET-MR

Advanced coronary artery plaque analysis, myocardial ischemia and coronary flow reserve


Locations(1)

Department of Clinical Science, University of Bergen

Bergen, Norway

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NCT05681858


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