RecruitingPhase 1NCT05683184

OMAR Opioid Use Disorder

Characterization of CB1 Receptors Using [11-C]OMAR in Opioid Use Disorder

Sponsor

Yale University

Enrollment

30 participants

Start Date

Mar 10, 2023

Study Type

INTERVENTIONAL

Conditions

Healthy Control Opioid-use Disorder

Summary

The goal of this research study is to examine the endocannabinoid (eCB) function in vivo in individuals with opioid use disorder (OUD) by measuring cannabinoid receptor 1 (CB1R) availability.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study (OMAR) uses brain imaging to understand how the brain is different in people with opioid use disorder (OUD) compared to healthy people, to help develop better treatments. You may be eligible if you: - Are 18 years of age or older - Have a DSM-5 diagnosis of opioid use disorder (if in the OUD group) - Are physically healthy with no unstable medical conditions You may NOT be eligible if you: - Have a current neuro-psychiatric illness or severe systemic disease - Have a pacemaker or ferromagnetic metal in your body - Have had previous radiation exposure close to the maximum recommended level - Have claustrophobia Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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