RecruitingNCT05685485

Tied Tube Trial in Glaucoma Surgery

The Effects of Temporary Tube Ligation in Ahmed Glaucoma Valve Surgery


Sponsor

Washington University School of Medicine

Enrollment

152 participants

Start Date

Oct 18, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this study is to assess whether delaying early flow through the Ahmed tube shunt may improve the post-operative surgical outcomes and provide a more predictable outcome. To assess this the investigator will conduct a, randomized prospective, multi-centered study with collaborators at WashU in St. Louis, Duke University, Indiana University and the University of Pittsburgh. Participants will be randomized to have an AGV placement with tube ligation (no-early flow) and without ligation (allowing for early flow). IOP will be measured at day one, week one, and months, one, three six, and twelve. Additionally, clinical data regarding number of glaucoma medications, and complications post-operative complications will also be collected.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Standard Implantation and a procedure called Tied off Tube for people with ahmed glaucoma valve implantation and glaucoma eye. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREStandard Implantation

Traditional Ahmed plantation without vicryl ligature

PROCEDURETied off Tube

Ahmed implantation with vicryl ligature


Locations(1)

Washington University

St Louis, Missouri, United States

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NCT05685485


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