RecruitingNot ApplicableNCT06607705

Changes in Eye Pressure in Glaucoma Patients Treated with Istent Inject W, Monitored by a Contact Lens Sensor

Fluctuations of the Intraocular Pressure in Surgically Treated Glaucoma Patients with IStent Inject W by a Contact Lens Sensor


Sponsor

Fundacio Privada Mon Clinic Barcelona

Enrollment

53 participants

Start Date

Oct 21, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to compare the IOP-related fluctuations using the CLS (contact lens sensor) Sensimed Triggerfish in glaucoma patients before and after glaucoma surgery with iStent inject W under physiological conditions and compare these results with a control group of glaucoma patients treated only with hypotensive medical treatment requiring cataract surgery.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Adult Patients (over 18 years old) with an initial diagnosis of POAG requiring an indication from the patient chart of an untreated IOP of over 21 mm Hg. Diagnosis of NTG requiring an untreated mean diurnal IOP of over 21 mm Hg from diagnosis to enrollment, indicated by the patient chart. Ocular hypertension is defined as a condition in which the IOP was greater than 21 mm Hg in the absence of glaucomatous defects in visual field testing, the normal appearance of the optic disc and nerve fiber layer, anatomic normality, open angles in gonioscopy, and the absence of ocular conditions contributing to the elevation of pressure, such as narrow angles, neovascular conditions, and uveitis.
  • Adult Patients (over 18 years old ) diagnosed with POAG and NTG are defined as those with open normal appearing angles, typical glaucomatous optic atrophy (i.e., neural rim thinning, notching, saucerization, or nerve fiber layer disc haemorrhage), and typical glaucomatous visual field damage (i.e., arcuate, paracentral scotoma, or nasal step).
  • Adult Patients (age over 18 years old ):
  • with unilateral or bilateral open-angle glaucoma (POAG) without previous eye surgery, treated with topical anti-glaucoma medications, who need glaucoma surgery with iStent inject W. The investigators will include patients with isolate iStent surgery and patients with combined cataract and iStent surgery. In cases of bilateral glaucoma, the two eyes of the same patient may be included consecutively.
  • For the control group only: Patients with topical hypotensive glaucoma treatment requiring cataract surgery.

Exclusion Criteria4

  • Age under 18 years
  • Visual defects attributable to nonglaucomatous conditions, primary angle closure glaucoma, neovascular glaucoma, history of ocular trauma, retinal disease or ocular inflammation, and laser therapy or secondary glaucoma.
  • The patients have to meet best-corrected Snellen visual acuity of under 0.3 and spherical equivalent of under 6 diopter.
  • We will not include patients with previous ocular surgery, except cataract surgery performed at least 6 months prior to the inclusion date.

Interventions

DEVICEMonitoring with contact lens sensor

Monitoring with contact lens sensor at 1-month pre-intervention visit

DEVICEMonitoring with contact lens sensor

Monitoring with contact lens sensor at 1-month post-intervention visit

DEVICEMonitoring with contact lens sensor

Monitoring with contact lens sensor at 3-months post-intervention visit


Locations(2)

Institut Català de Retina

Barcelona, Spain, Spain

Hospital Clínic de Barcelona

Barcelona, Spain, Spain

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NCT06607705


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