RecruitingNCT05687188

Evaluating Obesity-Mediated Mechanisms of Pancreatic Carcinogenesis in Minority Populations


Sponsor

H. Lee Moffitt Cancer Center and Research Institute

Enrollment

125 participants

Start Date

Feb 22, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This study will evaluate obesity-mediated mechanisms of pancreatic carcinogenesis in minority populations.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study investigates how obesity may increase the risk of pancreatic cancer, particularly in African American and Non-Hispanic White adults — two groups with different rates of pancreatic cancer. Participants provide tissue and blood samples during routine procedures. **You may be eligible if...** - You are 18 or older - You identify as African American or Non-Hispanic White - You are being evaluated at a participating clinic for a suspected or confirmed pancreatic tumor **You may NOT be eligible if...** - You are under 18 years old - There is no clinical suspicion or diagnosis of a pancreatic tumor - You identify with a race or ethnicity other than African American or Non-Hispanic White This is a research study collecting tissue and biological samples to understand cancer biology — not a treatment trial. Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERBlood Sample Collection

Participants will have 40 mL of blood drawn at baseline/pre-treatment. The study team will aim to have this blood collected at the time of standard of care blood draw if possible.

OTHERTissue Sample Collection

At the time of tissue biopsy or surgical resection (if applicable) pancreatic tumor tissue, fat, tissue from site of metastasis, and cyst fluid (if applicable) will be collected.

OTHERData Collection

Participants will complete a study questionnaire at baseline that includes medical history, lifestyle, and family history information.

OTHERMedical Image Collection

Medical images that are obtained during routine care such as computed tomography (CT) scans, magnetic resonance imaging (MRIs) and ultrasounds will be reviewed by the study team throughout the participant's medical care.


Locations(2)

Moffitt Cancer Center

Tampa, Florida, United States

University of Mississippi Medical Center

Jackson, Mississippi, United States

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NCT05687188


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