RecruitingNCT05693116

Survival and Prognostic Factors of Squamous Cell Carcinoma of the Nasal Vestibule

Survival and Prognostic Factors of Squamous Cell Carcinoma of the Nasal Vestibule: a Multi-centre Study

Sponsor

Istituto Clinico Humanitas

Enrollment

300 participants

Start Date

Dec 1, 2022

Study Type

OBSERVATIONAL

Conditions

Squamous Cell Carcinoma Nasal Vestibule Carcinoma Rhinectomy Nasal Vestibule

Summary

The goal of this observational study is to learn about survival and prognostic factors in patients who underwent surgical treatment for primary squamous cell carcinoma of the nasal vestibule. The main questions it aims to answer are: * what is the prognosis of patients affected by squamous cell carcinoma of the nasal vestibule? * are there any specific factors that could influence prognosis? * is it possible to elaborate a new staging system, able to overcome the limitations of the currently used ones? Data about patients, tumour and type of surgery performed will be collected. Participants will be followed-up for a minimum 6 months period after surgery.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study looks at survival outcomes and important prognostic factors in people who had surgery for squamous cell carcinoma of the nasal vestibule — a rare skin cancer located at the opening of the nose. **You may be eligible if...** - You were diagnosed with squamous cell carcinoma of the nasal vestibule - You received surgery with the goal of curing the cancer - Your medical and imaging records are available for review - You have been followed up for at least 6 months after surgery **You may NOT be eligible if...** - You were first seen for a cancer recurrence or persistence (not a new diagnosis) - Your tumor originated from nearby areas like the nasal cavity, nasal bridge, or upper lip — not the nasal vestibule itself Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURERhinectomy

Surgery will be performed according to extension of the tumour, i.e. local resection limited to the vestibule, partial rhinectomy, total rhinectomy, extended total rhinectomy