RecruitingNCT06384924

Raman Spectroscopy and Skin Cancer

Pilot Study of Raman Spectroscopic Imaging for Skin Cancer

Sponsor

Tiezhi Zhang

Enrollment

20 participants

Start Date

Feb 13, 2025

Study Type

OBSERVATIONAL

Conditions

Skin Cancer Basal Cell Carcinoma Squamous Cell Carcinoma

Summary

The goal of this observational study is to find out if Raman Spectroscopy, a type of imaging, can be used to determine the size of skin cancer tumors. The main question it aims to answer is: -Can Raman Spectroscopy help figure out how far a tumor spreads? This study will take measurements using laser light from an experimental, handheld probe by lightly touching the skin.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing Raman spectroscopy — a light-based measurement tool — to analyze skin cancer tissue during brachytherapy (a type of radiation treatment delivered from inside or directly on the skin) to see if it can help measure treatment effects in real time. **You may be eligible if...** - You have been diagnosed with basal cell carcinoma or squamous cell carcinoma (common forms of skin cancer) - You are scheduled to receive brachytherapy for your skin cancer at the study site - You can provide your own informed consent **You may NOT be eligible if...** - You are under 18 years old or unable to consent - Your cancer is on or near your eyelid - You are pregnant or of childbearing age and refuse pregnancy testing - You have a pacemaker Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICERaman Spectroscopy handheld probe (EmVision, FL, USA)

The probe is approximately the size of a pen or pencil. The handheld probe is connected to the laser source using a cable. The probe is placed in light contact with the skin. The features of the laser light after it bounces off the skin is collected. This measurement can allow us to see tissue characteristics. This is a single session that will take approximately 15 minutes.

DEVICERaman Spectroscopy laser source (Hubner Photonics Inc, CA, USA)

This light source will create the laser light that will pass through the cable and through the handheld probe onto the skin.

Locations(1)

Stony Brook Hospital

Stony Brook, New York, United States

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