RecruitingEarly Phase 1NCT05701969

Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift


Sponsor

University of Virginia

Enrollment

50 participants

Start Date

May 30, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Anesthesiology residency requires extended and overnight shifts, which may negatively impact the quantity and quality of sleep. Previous studies have investigated the effect of night float shift work on anesthesiology resident sleep and performance and demonstrated that total sleep quantity and time spent in deep and rapid eye movement (REM) sleep were significantly reduced during night float and did not return to baseline after 3 nights of recovery. Melatonin is a hormone produced by the pineal gland, which regulates the circadian rhythm that governs sleep. Exogenous melatonin may be used as a sleep aid and is available over the counter in the United States. Melatonin is effective in realigning the circadian rhythm disorder caused by night shift work and increasing sleep duration; however, melatonin's effect on improving sleep in resident trainees has not been investigated. The investigators propose a prospective double-blinded randomized control trial to investigate the effect of melatonin on sleep quantity and quality in resident physicians assigned to a night float system.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Post-Graduate Year 1-5
  • Current enrollment in anesthesiology, general surgery, obstetrics and gynecology, general medicine, or pediatrics residency at the Unversity of Virginia

Exclusion Criteria9

  • Current use of sleep aids
  • Diagnosed sleep disorder
  • History of a pacemaker or other medical device.
  • pregnant or breast-feeding females
  • Bleeding disorders
  • Depression
  • High blood pressure
  • Seizure disorders
  • History of transplant on immunosuppression therapy.

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Interventions

DIETARY_SUPPLEMENTMelatonin

Melatonin

OTHERPlacebo

Placebo control


Locations(1)

University of Virginia

Charlottesville, Virginia, United States

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NCT05701969


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